It had to be heavy enough to get those forces generated but light enough to still be able to puppeteer it. In the end, they realized it all comes down to the eyes. BJH : The size of the eye is very important. If you look at Planet of the Apes, they did the eyes of Caesar so well you really feel the emotion.
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We had a lot of fun making sure that Mija could focus on getting that relationship, that emotional tie, as convincing as possible. His eyes were very impressive. Having given Okja eyes, large ears, and realistic skin, they still had to give it a personality. I simply want to make the audience think that this animal is something that could happen in the very near future, like five years from now. In reality, there are such animals being developed.
Genetically modified salmon has already been developed.
I think we can all relate to that slightly older dog that is just happy to tag along, lumbers a bit, with floppy ears, looking up over its brows. That was the personality we wanted to give Okja: just a very content Labrador inside a super-pig body. Already a subscriber? Log in or link your magazine subscription.
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Photo: Courtesy of Netflix. Tags: okja behind the scenes bong joon-ho erik de boer special effects new york magazine More. When samples are sent for parasitologic studies, laboratories often do not uniformly perform tests to detect Cryptosporidium which requires specialized techniques, including modified acid-fast or fluorescent staining, antigen detection, or polymerase chain reaction [PCR] [ 8 ].
Studies using PCR have documented increased rates of detection of Cryptosporidium. In addition, PCR studies have documented increased rates of Cryptosporidium in diarrhea in people from wealthy countries [ 11 ]. Clearly, better diagnostic tests that carry the sensitivity of PCR but do not require specialized procedures or technology are needed. In addition to the role of cryptosporidiosis in diarrhea, there is some evidence of extraintestinal involvement with cryptosporidiosis. This complication is even more frequent in patients with hyper-immunoglobulin M syndrome.
Respiratory cryptosporidiosis is also a rarely recognized complication of cryptosporidiosis in patients with AIDS. Although cough is a common concern of childhood cryptosporidiosis, few data are available on the cause and on whether it is due to respiratory tract infection. In this context, Mor et al [ 15 ] studied children who presented with diarrhea to an acute care unit in Uganda.
After excluding patients with vomiting who might have aspirated the organisms, the authors induced sputum from 48 children with diarrhea and cryptosporidiosis and respiratory symptoms.
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In some cases, the respiratory symptoms preceded the onset of diarrhea. This is the first demonstration of respiratory cryptosporidiosis in apparently immunocompetent children. These data suggest that Cryptosporidium may be a respiratory pathogen, which raises a series of new questions.
Is the cough in cryptosporidiosis due to respiratory tract infection? What is the route of infection: aspiration from a primary gastrointestinal infection, hematogenous spread, or primary respiratory infection? Does cryptosporidiosis present as a primary respiratory infection, as opposed to a complication of intestinal disease? Does Cryptosporidium alter pulmonary function? What is the effect of treatment on respiratory cryptosporidiosis? All of these questions have bearing on the burden of disease due to this organism.
However, none of these questions would have been asked if novel techniques, such as PCR, were not being applied to an infection that we thought we understood. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.
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Urban Dictionary: Ears of the Hippo
Close mobile search navigation Article Navigation. Volume Article Contents. Cryptosporidiosis and the Ears of the Hippopotamus A. Clinton White, Jr. Reprints or correspondence: Dr A. Oxford Academic. Google Scholar. Cite Citation. Permissions Icon Permissions. Acknowledgments Potential conflicts of interest. References 1. Google Preview. Persistent diarrhea signals a critical period of increased diarrhea burdens and nutritional shortfalls: a prospective cohort study among children in northeastern Brazil.
Early childhood diarrhea is associated with diminished cognitive function 4 to 7 years later in children in a northeast Brazilian shantytown. The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. A massive outbreak of cryptosporidium infection transmitted through the public water supply.